I te tau 1968, i whakaahuahia e Kruger-Theimer te whakamahinga o ngā tauira pharmacokinetic hei hoahoa i ngā tikanga horopeta whai hua. Ko tēnei tikanga Bolus, Elimination, Transfer (BET) kei roto ko:
he horopeta bolus i tatauhia hei whakakī i te wāhanga pokapū (toto),
he werohanga auau pumau e ōrite ana ki te auau whakakorenga,
he werohanga hei whakakapi i te whakawhiti ki ngā kiko ā-taha: [te tere heke haere]
Ko te tikanga tuku iho ko te tatau i te tikanga werohanga mō te propofol mā te tikanga Roberts. Whai muri i te werohanga o te 1.5 mg/kg, ka werohia te 10 mg/kg/haora ki te 8 me te 6 mg/kg/haora i ia tekau meneti.
Te whai pānga ki te arotahi pae
Ngā pānga matua orongoā whakangoteKo ngā rongoā werohanga ko ngā pānga whakamoe me te whakamoe, ā, ko te wāhi e puta ai ēnei pānga o te rongoā, e kiia nei ko te wāhi pānga, ko te roro. Engari, kāore e taea te ine i te kukū o te roro [wāhi pānga] i roto i te mahi haumanu. Ahakoa ka taea e tātou te ine tika i te kukū o te roro, me mōhio tonu ki ngā kukū ā-rohe, ki ngā kukū rānei o te kaiwhakawhiwhi i te wāhi e puta ai te pānga o te rongoā.
Te whakatutuki i te kukū propofol pumau
E whakaatu ana te hoahoa i raro nei i te tere werohanga e hiahiatia ana i te tere heke tere i muri i te horopeta bolus hei pupuri i te kukū toto pumau o te propofol. E whakaatu ana hoki i te whakaroa i waenga i te toto me te kukū o te wāhi pānga.
Wā tuku: Whiringa-ā-rangi-05-2024